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While one baby in the SUSTAIN 5 trial was born with no known congenital abnormalities after the mother received semaglutide for about 9 weeks, there were two notable cases in the STEP trials
Makary singled out the ad in last week's Journal of the American Medical Association, calling it a "brazen" example of how advertising is "contributing to America's culture of overreliance on pharmaceuticals for health." Hims and similar companies initially sold cheap generic versions of drugs for hair loss, erectile dysfunction and other health issues
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But what exactly are GLP-1s
It is caused by the interplay between endothelial cells, vascular smooth muscle and macrophages
69 In comparison, newer oral small-molecule GLP-1 RAs, such as danuglipron and orforglipron, have demonstrated similar efficacy
